Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative σ factor, SigH

The pathogenesis of tuberculosis involves multiple phases and is believed to involve both a carefully deployed series of adaptive bacterial virulence factors and inappropriate host immune responses that lead to tissue damage. A defined Mycobacterium tuberculosis mutant strain lacking the sigH-encode...

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Autors principals: Kaushal, Deepak, Schroeder, Benjamin G., Tyagi, Sandeep, Yoshimatsu, Tetsuyuki, Scott, Cherise, Ko, Chiew, Carpenter, Liane, Mehrotra, Jyoti, Manabe, Yukari C., Fleischmann, Robert D., Bishai, William R.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC123067/
https://ncbi.nlm.nih.gov/pubmed/12060776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102055799
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