Attenuation of Late-Stage Disease in Mice Infected by the Mycobacterium tuberculosis Mutant Lacking the SigF Alternate Sigma Factor and Identification of SigF-Dependent Genes by Microarray Analysis

The Mycobacterium tuberculosis alternate sigma factor, SigF, is expressed during stationary growth phase and under stress conditions in vitro. To better understand the function of SigF we studied the phenotype of the M. tuberculosis ΔsigF mutant in vivo during mouse infection, tested the mutant as a...

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Detalhes bibliográficos
Main Authors: Geiman, Deborah E., Kaushal, Deepak, Ko, Chiew, Tyagi, Sandeep, Manabe, Yukari C., Schroeder, Benjamin G., Fleischmann, Robert D., Morrison, Norman E., Converse, Paul J., Chen, Ping, Bishai, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356042/
https://ncbi.nlm.nih.gov/pubmed/14977982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1733-1745.2004
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