Attenuation of Late-Stage Disease in Mice Infected by the Mycobacterium tuberculosis Mutant Lacking the SigF Alternate Sigma Factor and Identification of SigF-Dependent Genes by Microarray Analysis

The Mycobacterium tuberculosis alternate sigma factor, SigF, is expressed during stationary growth phase and under stress conditions in vitro. To better understand the function of SigF we studied the phenotype of the M. tuberculosis ΔsigF mutant in vivo during mouse infection, tested the mutant as a...

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Main Authors: Geiman, Deborah E., Kaushal, Deepak, Ko, Chiew, Tyagi, Sandeep, Manabe, Yukari C., Schroeder, Benjamin G., Fleischmann, Robert D., Morrison, Norman E., Converse, Paul J., Chen, Ping, Bishai, William R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Molecular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC356042/
https://ncbi.nlm.nih.gov/pubmed/14977982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.3.1733-1745.2004
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