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Glioma-initiating Cells Retain Their Tumorigenicity through Integration of the Sox Axis and Oct4 Protein

Although the concept of cancer stem cells or cancer-initiating cells had created a new paradigm for the treatment of malignant tumors, it remains unclear how cancer-initiating cells can be eradicated. We have previously reported that the transforming growth factor-β (TGF-β)-Sox4-Sox2 pathway is esse...

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Bibliografische gegevens
Hoofdauteurs: Ikushima, Hiroaki, Todo, Tomoki, Ino, Yasushi, Takahashi, Masamichi, Saito, Nobuhito, Miyazawa, Keiji, Miyazono, Kohei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308855/
https://ncbi.nlm.nih.gov/pubmed/21987575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.300863
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