SIRT2‐mediated inactivation of p73 is required for glioblastoma tumorigenicity

Glioblastoma is one of the most aggressive forms of cancers and has a poor prognosis. Genomewide analyses have revealed that a set of core signaling pathways, the p53, RB, and RTK pathways, are commonly deregulated in glioblastomas. However, the molecular mechanisms underlying the tumorigenicity of...

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Vydáno v:EMBO Rep
Hlavní autoři: Funato, Kosuke, Hayashi, Tomoatsu, Echizen, Kanae, Negishi, Lumi, Shimizu, Naomi, Koyama‐Nasu, Ryo, Nasu‐Nishimura, Yukiko, Morishita, Yasuyuki, Tabar, Viviane, Todo, Tomoki, Ino, Yasushi, Mukasa, Akitake, Saito, Nobuhito, Akiyama, Tetsu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216266/
https://ncbi.nlm.nih.gov/pubmed/30213795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745587
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