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Response Gene to Complement 32 Is Essential for Fibroblast Activation in Renal Fibrosis
Response gene to complement 32 (RGC-32) is a downstream target of transforming growth factor-β (TGF-β). TGF-β is known to play a pathogenic role in renal fibrosis. In this study, we investigated RGC-32 function in renal fibrosis following unilateral ureteral obstruction (UUO) in mice, a model of pro...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308844/ https://ncbi.nlm.nih.gov/pubmed/21990365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259184 |
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