Response Gene to Complement 32 Is Essential for Fibroblast Activation in Renal Fibrosis

Response gene to complement 32 (RGC-32) is a downstream target of transforming growth factor-β (TGF-β). TGF-β is known to play a pathogenic role in renal fibrosis. In this study, we investigated RGC-32 function in renal fibrosis following unilateral ureteral obstruction (UUO) in mice, a model of pro...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Zuguo, Xie, Wei-Bing, Escano, Crisanto S., Asico, Laureano D., Xie, Qiyun, Jose, Pedro A., Chen, Shi-You
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Molecular Bases of Disease
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308844/
https://ncbi.nlm.nih.gov/pubmed/21990365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259184
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