Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia

Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly known. We have studied the post-transcriptional changes in the proteome of mammalian cells elicited by acute hypoxia and found that phosphorylation of eukaryotic elongation fact...

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Detalles Bibliográficos
Autores principales: Romero-Ruiz, Antonio, Bautista, Lucía, Navarro, Virginia, Heras-Garvín, Antonio, March-Díaz, Rosana, Castellano, Antonio, Gómez-Díaz, Raquel, Castro, María J., Berra, Edurne, López-Barneo, José, Pascual, Alberto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308822/
https://ncbi.nlm.nih.gov/pubmed/22308030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299180
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