Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia

Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly known. We have studied the post-transcriptional changes in the proteome of mammalian cells elicited by acute hypoxia and found that phosphorylation of eukaryotic elongation fact...

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Main Authors: Romero-Ruiz, Antonio, Bautista, Lucía, Navarro, Virginia, Heras-Garvín, Antonio, March-Díaz, Rosana, Castellano, Antonio, Gómez-Díaz, Raquel, Castro, María J., Berra, Edurne, López-Barneo, José, Pascual, Alberto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308822/
https://ncbi.nlm.nih.gov/pubmed/22308030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299180
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