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The Trans-autostimulatory Activity of Rad27 Suppresses dna2 Defects in Okazaki Fragment Processing

Dna2 and Rad27 (yeast Fen1) are the two endonucleases critical for Okazaki fragment processing during lagging strand DNA synthesis that have been shown to interact genetically and physically. In this study, we addressed the functional consequences of these interactions by examining whether purified...

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Bibliografiska uppgifter
Huvudupphovsmän: Munashingha, Palinda Ruvan, Lee, Chul-Hwan, Kang, Young-Hoon, Shin, Yong-Keol, Nguyen, Tuan Anh, Seo, Yeon-Soo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308799/
https://ncbi.nlm.nih.gov/pubmed/22235122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326470
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