Rad52/Rad59-dependent Recombination as a Means to Rectify Faulty Okazaki Fragment Processing

The correct removal of 5′-flap structures by Rad27 and Dna2 during Okazaki fragment maturation is crucial for the stable maintenance of genetic materials and cell viability. In this study, we identified RAD52, a key recombination protein, as a multicopy suppressor of dna2-K1080E, a lethal helicase-n...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Miju, Lee, Chul-Hwan, Demin, Annie Albert, Munashingha, Palinda Ruvan, Amangyeld, Tamir, Kwon, Buki, Formosa, Tim, Seo, Yeon-Soo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
DNA and Chromosomes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031557/
https://ncbi.nlm.nih.gov/pubmed/24711454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.548388
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