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The Trans-autostimulatory Activity of Rad27 Suppresses dna2 Defects in Okazaki Fragment Processing

Dna2 and Rad27 (yeast Fen1) are the two endonucleases critical for Okazaki fragment processing during lagging strand DNA synthesis that have been shown to interact genetically and physically. In this study, we addressed the functional consequences of these interactions by examining whether purified...

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Bibliographische Detailangaben
Hauptverfasser: Munashingha, Palinda Ruvan, Lee, Chul-Hwan, Kang, Young-Hoon, Shin, Yong-Keol, Nguyen, Tuan Anh, Seo, Yeon-Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308799/
https://ncbi.nlm.nih.gov/pubmed/22235122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326470
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