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Insights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) Protein

The barrel-shaped caseinolytic protease P (ClpP) is a main virulence regulator in the bacterial pathogen Staphylococcus aureus (SaClpP). It consists of two heptameric rings forming a homotetradecamer with an inner chamber that houses the 14 active sites. We recently showed that SaClpP is able to ado...

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Autors principals: Gersch, Malte, List, Anja, Groll, Michael, Sieber, Stephan A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308785/
https://ncbi.nlm.nih.gov/pubmed/22291011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336222
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