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Identification of a Region That Assists Membrane Insertion and Translocation of the Catalytic Domain of Bordetella pertussis CyaA Toxin

The adenylate cyclase (CyaA) toxin, one of the virulence factors secreted by Bordetella pertussis, the pathogenic bacteria responsible for whooping cough, plays a critical role in the early stages of respiratory tract colonization by this bacterium. The CyaA toxin is able to invade eukaryotic cells...

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Détails bibliographiques
Auteurs principaux: Karst, Johanna C., Barker, Robert, Devi, Usha, Swann, Marcus J., Davi, Marilyne, Roser, Stephen J., Ladant, Daniel, Chenal, Alexandre
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308773/
https://ncbi.nlm.nih.gov/pubmed/22241477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.316166
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