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Amide Hydrogen/Deuterium Exchange & MALDI-TOF Mass Spectrometry Analysis of Pak2 Activation

Amide hydrogen/deuterium exchange (H/D exchange) coupled with mass spectrometry has been widely used to analyze the interface of protein-protein interactions, protein conformational changes, protein dynamics and protein-ligand interactions. H/D exchange on the backbone amide positions has been utili...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hsu, Yuan-Hao, Traugh, Jolinda A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308624/
https://ncbi.nlm.nih.gov/pubmed/22143461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3602
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