Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut

Neutrophils are innate immune cells that counter pathogens by many mechanisms including release of antimicrobial proteins such as calprotectin to inhibit bacterial growth. Calprotectin sequesters essential micronutrient metals such as zinc, thereby limiting their availability to microbes, a process...

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Huvudupphovsmän: Liu, Janet Z., Jellbauer, Stefan, Poe, Adam, Ton, Vivian, Pesciaroli, Michele, Kehl-Fie, Thomas, Restrepo, Nicole A., Hosking, Martin, Edwards, Robert A., Battistoni, Andrea, Pasquali, Paolo, Lane, Thomas E., Chazin, Walter J., Vogl, Thomas, Roth, Johannes, Skaar, Eric P., Raffatellu, Manuela
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308348/
https://ncbi.nlm.nih.gov/pubmed/22423963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.01.017
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