Inhibition of simian virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent.

An octathymidylate covalently linked via its 3'-end to an acridine derivative inhibited the cytopathic effect of Simian Virus SV40 on CV-1 cells in culture. Control experiments revealed that this effect was virus-specific and did not arise as a result of oligonucleotide degradation by nucleases. A p...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Birg, F, Praseuth, D, Zerial, A, Thuong, N T, Asseline, U, Le Doan, T, Hélène, C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1990
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2161517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.10.2901
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