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Enhanced SUMOylation and SENP-1 protein levels following oxygen and glucose deprivation in neurones
Here, we show that oxygen and glucose deprivation (OGD) causes increased small ubiquitin-like modifier (SUMO)-1 and SUMO-2/3 conjugation to substrate proteins in cultured hippocampal neurones. Surprisingly, the SUMO protease SENP-1, which removes SUMO from conjugated proteins, was also increased by...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308141/ https://ncbi.nlm.nih.gov/pubmed/21989481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.146 |
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