Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus

INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune disease accompanied by a disturbed T-cell balance skewed towards effector T-cells, in particular Th17-cells. The novel cytokine interleukin-21 (IL-21) is suggested to be crucial for triggering T-cell responses towards IL-17 producing...

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Main Authors: Dolff, Sebastian, Abdulahad, Wayel H, Westra, Johanna, Doornbos-van der Meer, Berber, Limburg, Pieter C, Kallenberg, Cees GM, Bijl, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308088/
https://ncbi.nlm.nih.gov/pubmed/21959034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3474
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