High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus

INTRODUCTION: High Mobility Group Box 1 (HMGB1) is a nuclear non-histone protein. HMGB1, which is secreted by inflammatory cells and passively released from apoptotic and necrotic cells, may act as a pro-inflammatory mediator. As apoptotic cells accumulate in systemic lupus erythematosus (SLE), HMGB...

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Autors principals: Abdulahad, Deena A, Westra, Johanna, Bijzet, Johannes, Limburg, Pieter C, Kallenberg, Cees GM, Bijl, Marc
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218880/
https://ncbi.nlm.nih.gov/pubmed/21548924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3332
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