Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA)

INTRODUCTION: The present study aimed to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis (GPA). METHODS: Peripheral blood from 42 GPA patients in remission and 29 age-matched healthy controls (HCs) were stimulated in vitro, and the f...

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Main Authors: Abdulahad, Wayel H, Lepse, Nikola, Stegeman, Coen A, Huitema, Minke G, Doornbos-van der Meer, Berber, Tadema, Henko, Rutgers, Abraham, Limburg, Pieter C, Kallenberg, Cees GM, Heeringa, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060544/
https://ncbi.nlm.nih.gov/pubmed/23799890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4247
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