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Integrins and their ligands in rheumatoid arthritis

Integrins play an important role in cell adhesion to the extracellular matrix and other cells. Upon ligand binding, signaling is initiated and several intracellular pathways are activated. This leads to a wide variety of effects, depending on cell type. Integrin activation has been linked to prolife...

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Detalhes bibliográficos
Main Authors: Lowin, Torsten, Straub, Rainer H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308078/
https://ncbi.nlm.nih.gov/pubmed/22077951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3464
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