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A genome-wide scan for common variants affecting the rate of age-related cognitive decline

Age-related cognitive decline is likely promoted by accumulated brain injury due to chronic conditions of aging, including neurodegenerative and vascular disease. Since common neuronal mechanisms may mediate the adaptation to diverse cerebral insults, we hypothesized that susceptibility for age-rela...

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Hlavní autoři: De Jager, Philip L., Shulman, Joshua M., Chibnik, Lori B., Keenan, Brendan T., Raj, Towfique, Wilson, Robert S., Yu, Lei, Leurgans, Sue E., Tran, Dong, Aubin, Cristin, Anderson, Christopher D., Biffi, Alessandro, Corneveaux, Jason J., Huentelman, Matthew J., Rosand, Jonathan, Daly, Mark J., Myers, Amanda J., Reiman, Eric M., Bennett, David A., Evans, Denis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307898/
https://ncbi.nlm.nih.gov/pubmed/22054870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.09.033
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