CR1 is associated with amyloid plaque burden and age-related cognitive decline

OBJECTIVE: Recently, genome-wide association studies have identified three new susceptibility loci for Alzheimer’s disease (AD), CLU, CR1, and PICALM. We leveraged available neuropsychological and autopsy data from two cohort studies to investigate whether these loci are associated with cognitive de...

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Detalhes bibliográficos
Main Authors: Chibnik, Lori B., Shulman, Joshua M., Leurgans, Sue E., Schneider, Julie A., Wilson, Robert S., Tran, Dong, Aubin, Cristin, Buchman, Aron S., Heward, Christopher B., Myers, Amanda J., Hardy, John A., Huentelman, Matthew J., Corneveaux, Jason J., Reiman, Eric M., Evans, Denis A., Bennett, David A., De Jager, Philip L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066288/
https://ncbi.nlm.nih.gov/pubmed/21391232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22277
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