Endogenously Determined Restriction of Food Intake Overcomes Excitation-Contraction Uncoupling in JP45KO Mice with Aging

The decline in muscular strength with age is disproportionate to the loss in total muscle mass that causes it. Knocking out JP45, an integral protein of the junctional face membrane of the skeletal muscle sarcoplasmic reticulum (SR), results in decreased expression of the voltage-gated Ca(2+) channe...

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Bibliographische Detailangaben
Hauptverfasser: Delbono, Osvaldo, Messi, Maria Laura, Wang, Zhong-Min, Treves, Susan, Mosca, Barbara, Bergamelli, Leda, Nishi, Miyuki, Takeshima, Hiroshi, Shi, Hang, Xue, Bingzhong, Zorzato, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307889/
https://ncbi.nlm.nih.gov/pubmed/22297108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.01.004
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