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Mild Hypothermia Decreases Fentanyl and Midazolam Steady-State clearance in a Rat Model of Cardiac Arrest

OBJECTIVES: Therapeutic hypothermia is widely-employed for neuroprotection after cardiac arrest(CA). However, concern regarding elevated drug concentrations during hypothermia and increased adverse drug reaction risk complicates concurrent pharmacotherapy. Many commonly used medications in criticall...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Empey, Philip E., Miller, Tricia M., Philbrick, Ashley H., Melick, John, Kochanek, Patrick M., Poloyac, Samuel M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307845/
https://ncbi.nlm.nih.gov/pubmed/22067624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31823779f9
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