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A Deadenylase Assay by Size-Exclusion Chromatography

The shortening of the 3′-end poly(A) tail, also called deadenylation, is crucial to the regulation of mRNA processing, transportation, translation and degradation. The deadenylation process is achieved by deadenylases, which specifically catalyze the removal of the poly(A) tail at the 3′-end of euka...

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Bibliografiske detaljer
Main Authors: He, Guang-Jun, Yan, Yong-Bin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307757/
https://ncbi.nlm.nih.gov/pubmed/22442711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033700
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