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A Deadenylase Assay by Size-Exclusion Chromatography

The shortening of the 3′-end poly(A) tail, also called deadenylation, is crucial to the regulation of mRNA processing, transportation, translation and degradation. The deadenylation process is achieved by deadenylases, which specifically catalyze the removal of the poly(A) tail at the 3′-end of euka...

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Bibliographic Details
Main Authors: He, Guang-Jun, Yan, Yong-Bin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307757/
https://ncbi.nlm.nih.gov/pubmed/22442711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033700
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