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A Deadenylase Assay by Size-Exclusion Chromatography

The shortening of the 3′-end poly(A) tail, also called deadenylation, is crucial to the regulation of mRNA processing, transportation, translation and degradation. The deadenylation process is achieved by deadenylases, which specifically catalyze the removal of the poly(A) tail at the 3′-end of euka...

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Detalhes bibliográficos
Main Authors: He, Guang-Jun, Yan, Yong-Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307757/
https://ncbi.nlm.nih.gov/pubmed/22442711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033700
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