Detecting base pair substitutions in DNA fragments by temperature-gradient gel electrophoresis.
A vertical gel electrophoresis apparatus is described which can distinguish DNA fragments differing by single base pair substitutions. The system employs a homogenous polyacrylamide gel containing urea-formamide and a temperature gradient which runs either perpendicular or parallel to the direction...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1990
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2339057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.9.2699 |
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