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Detecting base pair substitutions in DNA fragments by temperature-gradient gel electrophoresis.
A vertical gel electrophoresis apparatus is described which can distinguish DNA fragments differing by single base pair substitutions. The system employs a homogenous polyacrylamide gel containing urea-formamide and a temperature gradient which runs either perpendicular or parallel to the direction...
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| Hoofdauteurs: | , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1990
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330754/ https://ncbi.nlm.nih.gov/pubmed/2339057 |
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