The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels

BACKGROUND: A loss of function of the L-type calcium channel, Cav1.2, results in a cardiac specific disease known as Brugada syndrome. Although many Brugada syndrome channelopathies reduce channel function, one point mutation in the N-terminus of Cav1.2 (A39V) has been shown to elicit disease a phen...

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Bibliografiske detaljer
Main Authors: Simms, Brett A, Zamponi, Gerald W
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307476/
https://ncbi.nlm.nih.gov/pubmed/22385640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-9
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