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The Brugada syndrome mutation A39V does not affect surface expression of neuronal rat Cav1.2 channels
BACKGROUND: A loss of function of the L-type calcium channel, Cav1.2, results in a cardiac specific disease known as Brugada syndrome. Although many Brugada syndrome channelopathies reduce channel function, one point mutation in the N-terminus of Cav1.2 (A39V) has been shown to elicit disease a phen...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307476/ https://ncbi.nlm.nih.gov/pubmed/22385640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-9 |
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