Spatial association of the Cav1.2 calcium channel with α(5)β(1)-integrin

Engagement of α(5)β(1)-integrin by fibronectin (FN) acutely enhances Cav1.2 channel (Ca(L)) current in rat arteriolar smooth muscle and human embryonic kidney cells (HEK293-T) expressing Ca(L). Using coimmunoprecipitation strategies, we show that coassociation of Ca(L) with α(5)- or β(1)-integrin in...

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Autores principales: Chao, Jun-Tzu, Gui, Peichun, Zamponi, Gerald W., Davis, George E., Davis, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
Materias:
Membrane Transporters, Ion Channels and Pumps
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063962/
https://ncbi.nlm.nih.gov/pubmed/21178109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00171.2010
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