Acridine Yellow G Blocks Glioblastoma Growth via Dual Inhibition of Epidermal Growth Factor Receptor and Protein Kinase C Kinases

Amplification of the epidermal growth factor receptor (EGFR), frequently expressed as a constitutively active deletion mutant (EGFRvIII), occurs commonly in glioblastoma multiformes (GBM). However, blockade of EGFR is therapeutically disappointing for gliomas with PTEN deletion. To search for small...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Qi, Qi, He, Kunyan, Yoo, Min-Heui, Chan, Chi-Bun, Liu, Xia, Zhang, Zhaobin, Olson, Jeffrey J., Xiao, Ge, Wang, Liya, Mao, Hui, Fu, Haian, Tao, Hui, Ramalingam, Suresh S., Sun, Shi-Yong, Mischel, Paul S., Ye, Keqiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307261/
https://ncbi.nlm.nih.gov/pubmed/22215664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.293605
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