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Intramembrane Proton Binding Site Linked to Activation of Bacterial Pentameric Ion Channel
Prokaryotic orthologs of eukaryotic Cys-loop receptor channels recently emerged as structural and mechanistic surrogates to investigate this superfamily of intercellular signaling proteins. Here, we examine proton activation of the prokaryotic ortholog GLIC using patch clamp electrophysiology, mutag...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307256/ https://ncbi.nlm.nih.gov/pubmed/22084238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.305839 |
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