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The sva package for removing batch effects and other unwanted variation in high-throughput experiments

Summary: Heterogeneity and latent variables are now widely recognized as major sources of bias and variability in high-throughput experiments. The most well-known source of latent variation in genomic experiments are batch effects—when samples are processed on different days, in different groups or...

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Main Authors: Leek, Jeffrey T., Johnson, W. Evan, Parker, Hilary S., Jaffe, Andrew E., Storey, John D.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307112/
https://ncbi.nlm.nih.gov/pubmed/22257669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts034
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