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Effect of cholesterol nanodomains on the targeting of lipid-based gene delivery in cultured cells

Targeted gene delivery offers immense potential for clinical applications. Liposomes decorated with targeting ligands have been extensively used for both in vitro and in vivo gene delivery. Lipoplexes with high cholesterol content that result in cholesterol domain formation within the complexes have...

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Autors principals: Xu, Long, Anchordoquy, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307044/
https://ncbi.nlm.nih.gov/pubmed/20568694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100097b
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