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The effect of cholesterol domains on PEGylated liposomal gene delivery in vitro
AIM: PEGylated components have been widely used to reduce particle aggregation in serum and extend circulation lifetime for lipid- and polymer-based gene-delivery systems. However, PEGylation is known to interfere with cell interaction and intracellular trafficking, resulting in decreased biological...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303184/ https://ncbi.nlm.nih.gov/pubmed/22428082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.11.13 |
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