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The effect of cholesterol domains on PEGylated liposomal gene delivery in vitro

AIM: PEGylated components have been widely used to reduce particle aggregation in serum and extend circulation lifetime for lipid- and polymer-based gene-delivery systems. However, PEGylation is known to interfere with cell interaction and intracellular trafficking, resulting in decreased biological...

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Bibliografiske detaljer
Main Authors: Xu, Long, Wempe, Michael F, Anchordoquy, Thomas J
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303184/
https://ncbi.nlm.nih.gov/pubmed/22428082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.11.13
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