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Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition

Methods for fluorophore targeting to cellular proteins can allow imaging with dyes that are smaller, brighter, and more photostable than fluorescent proteins. Previously, we reported targeting of the blue fluorophore coumarin to cellular proteins fused to a 13-amino acid recognition sequence (LAP),...

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Autors principals: Yao, Jennifer Z., Uttamapinant, Chayasith, Poloukhtine, Andrei, Baskin, Jeremy M., Codelli, Julian A., Sletten, Ellen M., Bertozzi, Carolyn R., Popik, Vladimir V., Ting, Alice Y.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306817/
https://ncbi.nlm.nih.gov/pubmed/22239252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208090p
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