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Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition

Methods for fluorophore targeting to cellular proteins can allow imaging with dyes that are smaller, brighter, and more photostable than fluorescent proteins. Previously, we reported targeting of the blue fluorophore coumarin to cellular proteins fused to a 13-amino acid recognition sequence (LAP),...

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Detalhes bibliográficos
Principais autores: Yao, Jennifer Z., Uttamapinant, Chayasith, Poloukhtine, Andrei, Baskin, Jeremy M., Codelli, Julian A., Sletten, Ellen M., Bertozzi, Carolyn R., Popik, Vladimir V., Ting, Alice Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306817/
https://ncbi.nlm.nih.gov/pubmed/22239252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208090p
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