Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway

Ficolins are thought to be pathogen-associated-molecular-pattern-(PAMP-) recognition molecules that function to support innate immunity. Like mannose-binding lectins (MBLs), most mammalian ficolins form complexes with MBL-associated serine proteases (MASPs), leading to complement activation via the...

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Autores principales: Endo, Yuichi, Iwaki, Daisuke, Ishida, Yumi, Takahashi, Minoru, Matsushita, Misao, Fujita, Teizo
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306798/
https://ncbi.nlm.nih.gov/pubmed/22523468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/105891
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