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Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma

Sonic hedgehog (Shh) signaling is critical during development and its aberration is common across the spectrum of human malignancies. In the cerebellum, excessive activity of the Shh signaling pathway is associated with the devastating pediatric brain tumor medulloblastoma. We previously demonstrate...

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Detalhes bibliográficos
Main Authors: Bhatia, Bobby, Potts, Chad R., Guldal, Cemile, Choi, SunPhil, Korshunov, Andrey, Pfister, Stefan, Kenney, Anna M., Nahlé, Zaher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306783/
https://ncbi.nlm.nih.gov/pubmed/22407012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0968-6
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