Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma

Sonic hedgehog (Shh) signaling is critical during development and its aberration is common across the spectrum of human malignancies. In the cerebellum, excessive activity of the Shh signaling pathway is associated with the devastating pediatric brain tumor medulloblastoma. We previously demonstrate...

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Bibliografiske detaljer
Main Authors: Bhatia, Bobby, Potts, Chad R., Guldal, Cemile, Choi, SunPhil, Korshunov, Andrey, Pfister, Stefan, Kenney, Anna M., Nahlé, Zaher A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306783/
https://ncbi.nlm.nih.gov/pubmed/22407012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0968-6
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