Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma

Sonic hedgehog (Shh) signaling is critical during development and its aberration is common across the spectrum of human malignancies. In the cerebellum, excessive activity of the Shh signaling pathway is associated with the devastating pediatric brain tumor medulloblastoma. We previously demonstrate...

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Autori principali: Bhatia, Bobby, Potts, Chad R., Guldal, Cemile, Choi, SunPhil, Korshunov, Andrey, Pfister, Stefan, Kenney, Anna M., Nahlé, Zaher A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2012
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306783/
https://ncbi.nlm.nih.gov/pubmed/22407012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0968-6
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