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p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor

Medulloblastoma, a brain tumor arising in the cerebellum, is the most common solid childhood malignancy. The current standard of care for medulloblastoma leaves survivors with life-long side effects. Gaining insight into mechanisms regulating transformation of medulloblastoma cells-of-origin may lea...

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Detalhes bibliográficos
Main Authors: Bhatia, Bobby, Malik, Arfa, Fernandez-L, Africa, Kenney, Anna M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055184/
https://ncbi.nlm.nih.gov/pubmed/21051932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.21.13441
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