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Echinomycin binding to the sequence CG(AT)nCG alters the structure of the central AT region.
DNA fragments containing the sequence CG(AT)nCG have been used in footprinting experiments to assess the effect of echinomycin, which binds to CG steps, on the structure of the central AT region. DNAase I normally cuts ApT much better than TpA; in the presence of the drug this preference is retained...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1990
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330668/ https://ncbi.nlm.nih.gov/pubmed/2336384 |
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