Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cancer cells are metabolically stressed during tumour progression due to limited tumour vascularity and resultant nutrient, growth factor and oxygen deficiency that can induce cell death and inhibit tumour growth. We demonstrate that Rab25, a small GTPase involved in endosomal recycling, that is gen...

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Main Authors: Cheng, Kwai Wa, Agarwal, Roshan, Mitra, Shreya, Lee, Ju-Seog, Carey, Mark, Gray, Joe W, Mills, Gordon B
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306554/
https://ncbi.nlm.nih.gov/pubmed/22253197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100193
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