Rab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress

Cancer cells are metabolically stressed during tumour progression due to limited tumour vascularity and resultant nutrient, growth factor and oxygen deficiency that can induce cell death and inhibit tumour growth. We demonstrate that Rab25, a small GTPase involved in endosomal recycling, that is gen...

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Bibliografiske detaljer
Main Authors: Cheng, Kwai Wa, Agarwal, Roshan, Mitra, Shreya, Lee, Ju-Seog, Carey, Mark, Gray, Joe W, Mills, Gordon B
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2012
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306554/
https://ncbi.nlm.nih.gov/pubmed/22253197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100193
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