Kras(G12D) and p53 mutation cause primary intra-hepatic cholangiocarcinoma

Intrahepatic cholangiocarcinoma (IHCC) is a primary cancer of the liver with a rising incidence and poor prognosis. Preclinical studies of the etiology and treatment of this disease are hampered by the relatively small number of available IHCC cell lines or genetically faithful animal models. Here w...

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Hauptverfasser: O’Dell, Michael R., Huang, Jing-Li, Whitney-Miller, Christa L., Deshpande, Vikram, Rothberg, Paul, Grose, Valerie, Rossi, Randall M., Zhu, Andrew X., Land, Hartmut, Bardeesy, Nabeel, Hezel, Aram F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306549/
https://ncbi.nlm.nih.gov/pubmed/22266220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3596
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