Role of RhoA Specific Guanine Exchange Factors in Regulation of Endomitosis in Megakaryocytes

Polyploidization can precede the development of aneuploidy in cancer. Polyploidization in megakaryocytes (Mk), in contrast, is a highly controlled developmental process critical for efficient platelet production via unknown mechanisms. Using primary cells, we demonstrate that the guanine exchange fa...

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Detaylı Bibliyografya
Asıl Yazarlar: Gao, Yuan, Smith, Elenoe, Ker, Elmer, Campbell, Phil, Cheng, Ee-chun, Zou, Siying, Lin, Sharon, Wang, Lin, Halene, Stephanie, Krause, Diane S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306542/
https://ncbi.nlm.nih.gov/pubmed/22387001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.12.019
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