EGFR Exon 19 Insertions: A New Family of Sensitizing EGFR Mutations in Lung Adenocarcinoma

PURPOSE: EGFR genotyping is now standard in the management of advanced lung adenocarcinoma, as this biomarker predicts marked benefit from treatment with EGFR tyrosine kinase inhibitors (TKIs). EGFR exon 19 insertions are a poorly described family of EGFR mutations, and their association with EGFR T...

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Main Authors: He, Mai, Capelletti, Marzia, Nafa, Khedoudja, Yun, Cai-Hong, Arcila, Maria E., Miller, Vincent A., Ginsberg, Michelle S., Zhao, Binsheng, Kris, Mark G., Eck, Michael J., Jänne, Pasi A., Ladanyi, Marc, Oxnard, Geoffrey R.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306520/
https://ncbi.nlm.nih.gov/pubmed/22190593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2361
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