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EGFR Exon 19 Insertions: A New Family of Sensitizing EGFR Mutations in Lung Adenocarcinoma

PURPOSE: EGFR genotyping is now standard in the management of advanced lung adenocarcinoma, as this biomarker predicts marked benefit from treatment with EGFR tyrosine kinase inhibitors (TKIs). EGFR exon 19 insertions are a poorly described family of EGFR mutations, and their association with EGFR T...

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Hlavní autoři: He, Mai, Capelletti, Marzia, Nafa, Khedoudja, Yun, Cai-Hong, Arcila, Maria E., Miller, Vincent A., Ginsberg, Michelle S., Zhao, Binsheng, Kris, Mark G., Eck, Michael J., Jänne, Pasi A., Ladanyi, Marc, Oxnard, Geoffrey R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306520/
https://ncbi.nlm.nih.gov/pubmed/22190593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-2361
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