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Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus
The ribonuclease H (RNase H) domain of retroviral reverse transcriptase (RT) plays a critical role in the life cycle by degrading the RNA strands of DNA/RNA hybrids. In addition, RNaseH activity is required to precisely remove the RNA primers from nascent (−) and (+) strand DNA. We report here three...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306455/ https://ncbi.nlm.nih.gov/pubmed/22366278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.02.006 |
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